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Bone Marrow-Derived Progenitors (Handbook of Experimental Pharmacology

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Product Details»
Book Publisher: Springer (August, 2007)
»ISBN: 3540689753»
Book author: Katalin Kauser, Andreas Michael ZeiherBook
Description:
There is excitement generated almost daily about the possible uses of stem cells to treat human disease. The ability of stem cells to acquire different desired phenotype has opened the door for a new discipline: regenerative medicine. Much of the interest for this purpose is generated by embryonic stem cells, but their use is still controversial for moral reasons as well as scientifically. Less controversial and readily available are the adult bone marrow-derived progenitors including hematopoietic stem cells, endothelial progenitors and mesenchymal stem cells. The ambitious goal of this volume is to provide - in chapters written by accomplished scientists and experts in their field - a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells.
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Principles of Immunopharmacology

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Principles of Immunopharmacologyby Frans P. Nijkamp, Michael J. Parnham (Editors)
Paperback: 662 pages
Publisher: Birkhauser; 2 edition (December 22, 2005)
ISBN: 3764358041Book
Description
This textbook provides a unique support in gaining essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The first section of the book, covering a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts. The second section on immunodiagnostics has been further expanded to describe widely used molecular techniques and is followed by a systematic coverage of drugs affecting the immune system, revised to cover recent developments. The book concludes with a chapter on immunotoxicology. This second edition continues the unique format dealing with four related topics in a single volume, obviating the need to refer to several different textbooks. New aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first edition

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Mayo Clinic Antimicrobial Therapy: Quick Guide

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John W. Wilson, Lynn Estes, "Mayo Clinic Antimicrobial Therapy: Quick Guide"Informa HealthCare 2008-05-22 ISBN: 1420085182 352 p PDF 1.5 MbDirect from infectious diseases experts at Mayo Clinic, comes a new pocket-sized guide to antimicrobial therapy for the way you treat patients. Up-to-date, with hundreds of antimicrobial drugs included, this innovative consult also includes valuable antimicrobial drug dosing recommendations not found in some therapeutic pocket references. Written in an easy-to-use format, the Mayo Clinic Antimicrobial Therapy: Quick Guide provides simplified treatment recommendations for specific syndromes helping clinicians around the world improve their quick ID consults for positive patient outcomes. Pediatric dosing also included.

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Antibiotic Policies: Fighting Resistance

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Ian M. Gould, Jos W.M. van der Meer, "Antibiotic Policies: Fighting Resistance"
ISBN: 0387708405 Publisher: Springer Pages: 286 2007 PDF 5.9MB
Antibiotic resistance has reached epidemic proportions in most hospitals and many communities around the world. While control methods have traditionally (and usually unsuccessfully) relied on preventing cross infection it is increasingly obvious that new solutions are needed. There is growing evidence that the solution will lie in more careful use of antibiotics in the future.The golden age of antibiotic therapy has gone, probably for good and prescribers (and society at large) will have to accept that, in future, antibiotics will not be the "cure all" we have been accustomed to. This book addresses many of the key issues taxing our society and hospitals in an era of epidemic resistance and shortage of new antibiotics. Written by internationally renowned experts in the field, this volume will provide practical advice and inform control strategies for the most urgent of problems related to antibiotic resistance epidemic for years to come. Antibiotic Policies: Fighting Resistance is an ideal volume for health professionals with an interest in this field.

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Glaucoma Medical Therapy: Principles and Management second edition 2008

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Glaucoma Medical Therapy: Principles and Management (American Academy of Ophthalmology Monograph Series)Oxford University Press, USA ISBN: 0195328507 2 Edition - 2008 PDF 312 pages 2.7 MB
rapidshare&Megauploadr]In recent years, a large number of drugs have been developed for the treatment of glaucoma. The clinical use of drugs for glaucoma therapy has evolved, adapting with the advent of each new drug. Clinicians need to understand, synthesize, and use data about medications that have specific benefits and risks for their glaucoma patients. The focus of this book is the current art and science of clinically available drugs for medical therapy of glaucoma. The contributors have attempted to provide evidence-based information about the topic, while providing perspective from clinical experience. The book is intended to provide information about glaucoma medical therapy for practicing ophthalmologists and ophthalmologists in training. Other practitioners who have clinical contact with glaucoma patients also may find the content of this monograph valuable. In the second edition of this book, all chapters have been thoroughly revised and updated, and new chapters regarding fixed combination drugs and medical treatment of pediatric patients have been added. Some chapters have required addition of extensive new material because of the changes in medical therapy of glaucoma since the publication of the first edition of the book in 1999.
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Drug Therapy for Gastrointestinal Disease

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Drug Therapy for Gastrointestinal Disease Publisher:Informa HealthCare Pages:300 2001-05 ISBN:1853177334 PDF 1.3 MBThis book is an invaluable clinical reference for the therapeutic management of gastrointestinal and liver diseases which the gastroenterologist and trainee encounter in their practice. Various drugs and their interactions with their intended site and also with other drugs are discussed from a practical point of view. This book is not a treatise on gastrointestinal pharmacology but a practical guide to the therapeutic use of GI drugs.

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Clinical Guide to the Use of Antithrombotic Drugs in Coronary Artery Disease

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Clinical Guide to the Use of Antithrombotic Drugs in Coronary Artery Disease Publisher:Informa HealthCare Pages:400 2008-04-08 ISBN:1841846392 PDF 5.1 MBAtherothrombotic disease is the leading cause of morbidity and mortality; therefore, anti-thrombotic agents play a pivotal role in primary and secondary prevention of atherothrombotic complications. In A Clinical Guide to the Use of Antithrombotic Drugs, three main sections in the field have been elaborated. In the first, 3 chapters on basics concepts of atherothrombosis are examined. The objectives of these chapters are to provide pathophysiological concepts on atherothrombosis useful to the practicing clinician to understand the rationale for using antithrombotic agents in daily practice. In the second section, 16 chapters describe 4 main categories of antithombotic agents used in clinical practice: oral antiplatelet agents, intravenous antiplatelet agents, thrombin inhibitors, and fibrinolytics. In each category, description and clinical application of currently approved agents as well as agents under clinical investigation are described. The objectives of this section are to provide the stateof the art knowledge on antithrombotic drug use and development. In the third section, a series of 8 chapters examines the application of antithrombotic agents in specific clinical scenarios. The objective of this section is to provide practical insights on how to apply antithrombotic agents in the context of daily clinical scenarios. Overall, this compendium provides a valuable tool for clinicians in their daily clinical practice on how to use currently available antithrombotic agents as well as provide insights on the future development in this field.

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Targeted Radionuclide Tumor Therapy: Biological Aspects

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Targeted Radionuclide Tumor Therapy: Biological AspectsPublisher: Springer Language: English ISBN:1402086954 402 pages Data: 2007 PDF 5 Mb


Description:
The last three decades have provided opportunities to explore the potential of treating malignant diseases with antibodies or other targeting molecules labelled with nuclides. The expanding array of new targeting molecules (recombinant antibodies or peptides) may increase the therapeutic efficacy. The title of this book "Targeted Radionuclide Tumor Therapy – Biological aspects" was selected to reinforce the concept that a major focus was devoted to understanding the biological effects of targeting and radiation. Furthermore, our rapidly expanding knowledge of low dose-rate effects, different types of cell death, autosensitization and the increasingly likely existence of cancer stem cells suggests to us that even more efficient approaches in targeting might be possible in the future.The development of targeted therapy is a true multidisciplinary enterprise involving physician scientists from the fields of nuclear medicine, radiation therapy, diagnostic radiology, surgery, gynaecology, pathology and medical oncology/haematology. It also involves many preclinical scientists working with experimental animal models, immunochemistry, recombinant antibody technologies, radiochemistry, radiation physics and basic cell biology.It is the ambition of the editors to enable deeper insights in the process of improving targeted therapy. We believe that the time now has come when targeted therapy can soon be added to standard oncology treatment regimens.


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Gene Therapy for Renal Diseases and Transplantation (2008)

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Gene Therapy for Renal Diseases and TransplantationPublisher: S. Karger AG Language: English ISBN: 3805585055 110 pages Data: 2008 PDF 2 Mb
Description:
Initially conceived as a strategy to remedy inherited genetic disorders, gene therapy has been successfully applied in the last decade to ameliorate the renal function compromised by progressive renal diseases and to prevent kidney allograft rejection in experimental animals. In the present book, world-renowned experts are presenting new insights into viral and non-viral systems used to effect gene delivery, one chapter being dedicated to the new field of RNA interference (RNAi). This latter method may be successfully used in renal ischemia-reperfusion injury, trauma and transplantation. In the near future, gene therapy might also prove to be a new strategy to target molecules involved in tissue damage and inflammation processes that underlie ARF. So far, gene transfer has been successfully applied in experimental glomerulonephritis and interstitial fibrosis, and studies in larger animals are keenly awaited. Also covered are issues related to transplantation, which is the therapy of choice in many end-stage organ failures. Transfer of genes whose protein products have immunomodulatory properties have proven beneficial in treating acute and chronic graft rejection, one of the problems not satisfactorily solved by current anti-rejection drugs. Gene therapy thus may become a reality in clinical transplantation once its efficacy in larger animals has been demonstrated. Last but not least, a possible benefit of targeted gene therapy in renal cancer or HIV-associated nephropathy is explored. Covering a wide spectrum of topics, this publication provides a valuable overview of current developments and issues.
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Fibrinolytic Therapy in Clinical Practice

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Fibrinolytic Therapy in Clinical Practice Publisher:Informa Healthcare Pages:256 2003-07-31 ISBN: 1841840815 PDF 2.7 MBOne of the major breakthroughs in the treatment of cardiovascular disease is the introduction of fibrinolytic therapy. Better knowledge of the pathogenesis of acute ischemic syndromes has identified acute thrombosis as the triggering event in most cases. Thrombosis of large and small arteries may have catastrophic consequences as sudden death, myocardial infarction, ischemic stroke, pulmonary embolism and acute limb necrosis. Fibrinolytic therapy is aimed at early restoration of occluded blood vessels, thus improving symptoms and organ recovery, reducing infarct size and improving quantity and quality of life. However, fibrinolytic drugs have severe, sometimes fatal side-effects. These center on bleeding, sometimes fatal cerebral bleeding. Therefore, stringent patient selection is mandatory; age, time to treatment, relative and absolute contraindications and comitant medication are of utmost importance for safe and efficacious fibrinolysis.

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WHO Model Prescribing Information: Drugs Used in Bacterial Infections

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WHO Model Prescribing Information: Drugs Used in Bacterial Infections Publisher:World Health Organisation Pages:184 2001-01-07 ISBN: 9241401079 PDF 6.9 MB
Provides model prescribing information for essential drugs used in the treatment of bacterial infections. This new volume includes drugs used for treating respiratory, gastrointestinal, urinary, perioral, dental and cardiovascular infections, as well as septicaemia and infections of the skin, soft tissues, bones and joints, sexually transmitted diseases, and other commonly encountered bacterial infections. It also covers prophylaxis against rheumatic fever, meningitis, and bacterial infection during surgery.

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Dermatology Therapy: A to Z Essentials

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Paperback: 700 pagesData: February 12, 2004Format: PDFDescription: This new title in the Springer series "A to Z Essentials" contains nearly 1000 entries on dermatologic definitions, differential diagnoses and therapeutic possibilities. The highly structured articles include succinct discussions of the signs, symptoms and therapeutic options, including designations of therapies of choice, where appropriate. The volume is richly illustrated in color and contains many tables outlining commonly used medications in dermatology for ease of reference.
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Pain Medicine and Management: Just the Facts

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Paperback: 416 pages
Data: May 7, 2004
Format: PDF
Description: A quick reference to the management of pain for specialists as well as general medical practitioners and residents. Written in a concise bulleted format, the content is limited to only the essential facts necessary for assessment and treatment of common pain conditions and presentations. A perfect review tool for both the anesthesia and pain medicine board exams.

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Viral Therapy of Human Cancers

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Viral Therapy of Human Cancers
Publisher:Informa HealthCare Pages:848 2004-12-28 ISBN:0824759133 PDF 6.2 MB

Featuring contributions from nearly 30 leading authorities, this pioneering work gauges the potential for viruses to act as oncolytic and anti-tumor agents for the treatment of cancers in humans-detailing the cancer-combative properties exhibited by viruses in nature, genetically engineered viruses, and viral oncolysates as evidenced in basic and experimental studies.




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Acid-Base Disorders and Their Treatment

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Acid-Base Disorders and Their Treatment
Publisher:Informa HealthCare Pages:880 2005-08-09 ISBN:082475915X PDF 10.3 MB

With detailed contributions and research from experts in the physiology of normal acid-base homeostasis and the management of acid-base disorders, this reference supplies an abundance of information on acid-base physiology, disorders of acid-base equilibrium, and the management and treatment of these disorders in clinical practice. A unique and timely source, this guide provides a large number of tables, references, and figures to illustrate the relationship between the underlying physiology and diagnosis of acid-base disorders.




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Pharmacology and Therapeutics of Cough (2008)

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Pharmacology and Therapeutics of Cough
Publisher: Springer Language: English ISBN: 3540798412 376 pages Data: 2008 PDF 6 Mb

Description: The last decade has seen remarkable advances in our knowledge of cough. This applies especially to its basic mechanisms: the types of airway sensors, the pharmacological receptors on their membranes, the brainstem organization of the ‘cough centre’, and the involvement of the cerebral cortex in the sensations and the voluntary control of cough. This book shows that basic studies are pointing to many potentially valuable approaches to the treatment of cough, based on understanding the basic peripheral receptor mechanisms, the brainstem pathways in the control of cough, and the sensitization processes that may apply in disease.


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Cancer Chemotherapy Drug Manual 2008

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Physician's Cancer Chemotherapy Drug Manual 2008
Jones and Bartlett Publishers Pages:552 2007-12-28 ISBN:0763755621 PDF 3 MB

Completely revised and updated for 2008, this practical handbook is an up-to-date guide to all aspects of cancer chemotherapy. The book provides a comprehensive, easy to use catalogue of over 100 drugs-both on- and off-label-commonly used in cancer treatment. A section on Common Chemotherapy Regimens provides a quick reference to management of specific cancers, arranged alphabetically.



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Drugs for the Treatment of Respiratory Diseases

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Drugs for the Treatment of Respiratory Diseases
Publisher:Cambridge University Press Pages:612 2003-03-24 ISBN: 0521773210 PDF 6.6 MB

Millions of people are affected by these diseases, and the re-emergence of tuberculosis and increase in asthma in certain populations underline the importance of finding effective treatments. The demographice make this a critical time to identify novel strategies to prevent and treat these increasingly common diseases. The volume surveys and evaluates the drug treatments available for the main categories of lung diseases, including asthma, tuberculosis, smoking disorders, lung cancer, and respiratory infections.



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Fundamentals of Clinical Psychopharmacology

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Fundamentals of Clinical Psychopharmacology, Second Edition
Publisher:Taylor & Francis Pages:170 2004-08-09 ISBN:1841844276 PDF 1.4 MB

This book brings together leading UK psychiatrists and psychopharmacologists to review and clarify essential information about the scientific background and clinical applications of the drugs used in psychiatry. Based on the excellent Psychopharmacology Course for Psychiatrists in Training, organized twice a year by the British Association for Psychopharmacology, Fundamentals of Clinical Psychopharmacology reflects the individual lectures that make up the course, ranging from basic neuroscience to the analysis of clinical trials. The book is updated regularly, and this Second Edition includes a helpful new chapter on child and adolescent psychopharmacology.


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Pharmacogenetics of Breast Cancer

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Pharmacogenetics of Breast Cancer: Towards the Individualization of Therapy
Publisher:Informa HealthCare Pages:352 2008-05-19 ISBN:1420052934 PDF 2.8 MB

Pharmacogenetics, generally referred to as the study of genetic variation that gives rise to differing response to drugs, is becoming more relevant in the diagnosis, treatment, and recovery of cancer patients. The problem faced when treating cancer is the outstanding varied efficacy between success and failure. Unpredictability between a population of patients who are affected with the same occurring malignancy can show varying associated toxicities in drug treatment ranging from zero effect through lethal doses. Since the chemotherapeutic agent is often developed to fit the average patient the unfortunate result is that approximately 40% of patients may be receiving the wrong drug. However, using pharmacogenetics there are promising advancements in the development of effective agents which will enable ‘personalized cancer chemotherapy’ to become routine for the clinical practice. This individualization is most advanced in the field of breast cancer; while many breast oncologists are individualizing techniques based on specific profiles, within 10 years it is likely all breast oncologists will be using RT-PCR, FISH-based multiplexed arrays, or a similar testing regime for patient individualization therapy.


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